Symptoms

Reduced C27 3beta-HSD activity in cultured fibroblasts

Reduced CD95-induced lymphocyte apoptosis

Reduced CSF asparagine concentration

Reduced CSF creatine concentration

Reduced CSF cystine concentration

Reduced CSF dopamine concentration

Reduced CSF lactate

Reduced CSF methionine concentration

Reduced CSF pyridoxal-5'-phosphate concentration

Reduced F-wave amplitude

Reduced FEV1/FVC ratio

Reduced HMG-CoA lyase activity in cultured fibroblasts

Reduced Inositol polyphosphate 5-phosphatase OCRL-1 activity in cultured fibroblasts

Reduced MHC I cell surface expression

Reduced MHC II cell surface expression

Reduced N-acetylgalactosamine-6-sulfatase in cultured fibroblasts

Reduced OCT-measured foveal thickness

Reduced OCT-measured macular thickness

Reduced T cell CD40 expression

Reduced TSH response to thyrotrophin-releasing hormone stimulation test

Reduced ability to form peer relationships

Reduced ability to move the eyes

Reduced acetaldehyde dehydrogenase level

Reduced acetylglucosamine-6-sulfatase activity in cultured fibroblasts

Reduced albumin

Reduced alkyl-dihydroxyacetonephosphate synthase activity in cultured fibroblasts

Reduced alpha-1-antitrypsin

Reduced alpha-2-antiplasmin activity

Reduced alpha-aminoadipic semialdehyde synthase activity in cultured fibroblasts

Reduced alpha-methylacyl-CoA racemase activity in cultured fibroblasts

Reduced alpha/beta synthesis ratio

Reduced amplitude of dark-adapted bright flash electroretinogram a-wave

Reduced amygdala volume

Reduced ankle mobility

Reduced anterior scleral thickness

Reduced antigen-specific T cell proliferation

Reduced antithrombin III activity

Reduced antithrombin antigen

Reduced antral follicle count

Reduced appetite

Reduced arm span

Reduced aromatase activity

Reduced aspartoacylase activity in cultured fibroblasts

Reduced attention regulation

Reduced awareness of convention

Reduced beta-hexosaminidase A activity

Reduced beta-hexosaminidase B activity

Reduced beta/alpha synthesis ratio

Reduced bifunctional protein activity

Reduced bladder capacity

Reduced blood 5-methyltetrahydrofolate level

Reduced blood folate concentration

Reduced blood urea nitrogen

Reduced bone growth

Reduced bone mineral density

Reduced bone-marrow megakaryocyte size

Reduced bone-marrow pro-B cell count

Reduced bowel sounds

Reduced brain N-acetyl aspartate level by MRS

Reduced brain choline level by MRS

Reduced brain creatine level by MRS

Reduced brain gamma-aminobutyric acid level by MRS

Reduced brain glutamate level by MRS

Reduced brain glutamine level by MRS

Reduced brain lactate level by MRS

Reduced branched-chain alpha-keto acid dehydrogenase activity in cultured fibroblasts

Reduced breast milk zinc concentration

Reduced cell surface marker level

Reduced cellular cobalamin uptake

Reduced cerebral white matter volume

Reduced circulating 3-hydroxyisobutyryl-CoA hydrolase activity

Reduced circulating 3-ketoacyl-CoA thiolase concentration

Reduced circulating 4-Hydroxyphenylpyruvate dioxygenase activity

Reduced circulating 5-oxoprolinase activity

Reduced circulating 6-pyruvoyltetrahydropterin synthase activity

Reduced circulating C-reactive protein concecntration

Reduced circulating CH50 activity

Reduced circulating acetylcarnitine concentration

Reduced circulating acyl-CoA oxidase activity

Reduced circulating acylcarnitine concentration

Reduced circulating adenosine deaminase-2 activity

Reduced circulating aldolase concentration

Reduced circulating alpha-1,3-fucosyltransferase activity

Reduced circulating alpha-1-antitrypsin concentration

Reduced circulating alpha-L-fucosidase activity

Reduced circulating aromatic L-amino acid decarboxylase activity

Reduced circulating aspartate aminotransferase concentration

Reduced circulating catalase activity

Reduced circulating cholinesterase activity

Reduced circulating complement concentration

Reduced circulating complement factor H related protein 1 concentration

Reduced circulating corticosteroid-binding globulin concentration

Reduced circulating creatine concentration

Reduced circulating dopamine beta-hydroxylase activity

Reduced circulating erythropoietin concentration

Reduced circulating fibroblast growth factor 23 concentration

Reduced circulating fibronectin level

Reduced circulating growth hormone concentration

Reduced circulating insulin-like growth factor 2 concentration

Reduced circulating interferon gamma concentration